Myasthenia Gravis

Myasthenia gravis is a muscle weakness disorder caused by faulty communication between nerves and muscles. This condition is known as a neuromuscular junction disorder, which includes myasthenia gravis, Lambert-Eaton syndrome, and congenital myasthenic syndromes. In myasthenia gravis, the immune system mistakenly attacks the receptors responsible for receiving nerve signals, leading to muscle weakness and fatigue. Myasthenia gravis can affect any muscle group in the body, but it most commonly affects the muscles controlling eye and eyelid movement, facial expression, chewing, swallowing, and breathing. 

The symptoms of myasthenia gravis vary from person to person and can range from mild to severe. The most common symptom is muscle weakness, which worsens with activity and improves with rest. Other symptoms may include double vision, drooping eyelids, difficulty speaking, difficulty swallowing, and shortness of breath. These symptoms can significantly impact a person's quality of life and ability to perform everyday tasks.

Currently, there is no cure for myasthenia gravis, but proper treatment and care can help manage the symptoms and help people lead more independent lives. The UCSF Myasthenia Gravis Clinic diagnoses and cares for people with neuromuscular junction disorders. This clinic is a one-stop shop where patients with these disorders can be evaluated, diagnosed, and treated. To ensure an accurate diagnosis, we perform physical exams, lab tests, and electrodiagnostic tests (used to measure electrical activity in nerves). Our neurologists work closely with other specialists – including neuro-ophthalmologists and thoracic surgeons – to develop custom-tailored treatment plans. To reduce symptoms, the healthcare team may use a class of agents called immunomodulators (drugs that impact how the immune system works). Other possible treatments include physical, speech, and respiratory therapy, all of which can improve quality of life. To visit this clinic, you'll need your doctor's referral.

 

Learn more about our UCSF Myasthenia Gravis Center.

Here are some resources for people with Myasthenia Gravis (MG):

  1. Myasthenia Gravis Foundation of America: This is a non-profit organization that provides education, support, and resources for people with MG and their families. They offer support groups, information on treatment options, and advocacy efforts to raise awareness about this condition.
  2. Muscular Dystrophy Association: The Muscular Dystrophy Association (MDA) offers resources and support for people with MG and their families. They provide information on managing symptoms, financial assistance, and access to medical equipment and services.
  3. National Institute of Neurological Disorders and Stroke: This is a division of the National Institutes of Health (NIH) that conducts and funds research on neurological disorders, including MG. They offer information on the latest research, clinical trials, and treatment options for MG.
  4. American Autoimmune Related Diseases Association: This is a non-profit organization that provides support, education, and advocacy for people with autoimmune diseases, including MG. They offer resources on managing symptoms, connecting with healthcare providers, and finding community support.
  5. Rare Disease United Foundation: This is a non-profit organization that advocates for people with rare diseases, including MG. They provide resources on accessing healthcare, finding clinical trials, and connecting with other people affected by MG.
  6. MG United: This is an online resource hub for people with MG and their caregivers. They offer information on managing symptoms, community support forums, and a directory of healthcare providers who specialize in treating MG. They also offer resources for mental health support and navigating insurance and financial issues related to MG treatment.